Dishevelled
| Dishevelled specific domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Solution structure of the mouse Dvl-1 DEP domain based on the PDB 1fsh coordinates. | |||||||||
| Identifiers | |||||||||
| Symbol | Dishevelled | ||||||||
| Pfam | PF02377 | ||||||||
| InterPro | IPR003351 | ||||||||
| PROSITE | PDOC50841 | ||||||||
| |||||||||
Dishevelled (Dsh) is a family of proteins involved in canonical and non-canonical Wnt signalling pathways. Dsh is a cytoplasmic phosphoprotein that acts directly downstream of frizzled receptors.
Dishevelled plays important roles in both the embryo and the adult, ranging from cellular differentiation and cell polarity to social behavior.
Members
There are three human genes that encode dishevelled proteins:
References
External links
Retrieved from : http://en.wikipedia.org/wiki/Dishevelled
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