5,10-Methenyltetrahydrofolate
| 5,10-Methenyltetrahydrofolate | |
|---|---|
| Identifiers | |
| CAS number | 7444-29-3 |
| PubChem | 644350 |
| ChemSpider | 133 |
| MeSH | 5,10-methenyltetrahydrofolate |
| ChEMBL | CHEMBL46521 |
| Jmol-3D images | Image 1 |
| Properties | |
| Molecular formula | C20H213N7O6 |
| Molar mass | 455.42 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
5,10-Methenyltetrahydrofolate (5,10-CH=THF) is a form of tetrahydrofolate that is an intermediate in metabolism. 5,10-CH=THF is a coenzyme that accepts and donates methenyl (CH=) groups.
It is produced from 5,10-methylenetetrahydrofolate by either a NAD+ dependent methylenetetrahydrofolate dehydrogenase, or a NADP+ dependent dehydrogense. It can also be produced as an intermediate in histidine catabolism, by formiminotransferase cyclodeaminase, from 5-formiminotetrahydrofolate.
5,10-CH=THF is a substrate for methenyltetrahydrofolate cyclohydrolase, which converts it into 10-formyltetrahydrofolate.
References
Retrieved from : http://en.wikipedia.org/wiki/5,10-Methenyltetrahydrofolate
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