2011/05/02

5,10-Methenyltetrahydrofolic acid

5,10-Methenyltetrahydrofolate

5,10-Methenyltetrahydrofolate
Identifiers
CAS number 7444-29-3
PubChem 644350
ChemSpider 133
MeSH 5,10-methenyltetrahydrofolate
ChEMBL CHEMBL46521
Jmol-3D images Image 1
Properties
Molecular formula C20H213N7O6
Molar mass 455.42 g/mol
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

5,10-Methenyltetrahydrofolate (5,10-CH=THF) is a form of tetrahydrofolate that is an intermediate in metabolism. 5,10-CH=THF is a coenzyme that accepts and donates methenyl (CH=) groups.

It is produced from 5,10-methylenetetrahydrofolate by either a NAD+ dependent methylenetetrahydrofolate dehydrogenase, or a NADP+ dependent dehydrogense. It can also be produced as an intermediate in histidine catabolism, by formiminotransferase cyclodeaminase, from 5-formiminotetrahydrofolate.

5,10-CH=THF is a substrate for methenyltetrahydrofolate cyclohydrolase, which converts it into 10-formyltetrahydrofolate.

References






Retrieved from : http://en.wikipedia.org/wiki/5,10-Methenyltetrahydrofolate

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